Our laboratory works with cyanobacteria to improve industrial manufacturing and environmental characterization. We work with two strains, Synechococcus sp. PCC 7002 and Trichodesmium erythraeum to purse these goals.
S. sp. PCC 7002 is a naturally competent organism, meaning that it can spontaneously uptake foreign DNA, but is still prone to a plethora of engineering and design concerns. We are attempting to:
- Improve gene delivery techniques,
- Characterize metabolic adaptations to genetic and environmental perturbations, and
- Implement best design strategies to reduce collateral metabolic effects.
A more comprehensive overview can be found here.
Trichodesmium erythraeum is a ubiquitous, significant nitrogen and carbon fixer in the ocean. We are attempting to improve its laboratory characterization to extend to in situ environments.